Medication-assisted treatment (MAT) is the use of medications in combination with counseling and behavioral therapies for treating opioid addiction. It can also help some people to sustain recovery. Established evidence indicates that MAT is a highly effective approach to preventing overdoses and death for people living with opioid addiction.MAT consists of the following commonly used medications:MethadoneMethadone is a synthetic opioid medication that reduces withdrawal symptoms in people addicted to heroin or other narcotics without causing the "high" associated with problem drug use. Methadone stabilizes people. This helps maximize their treatment and recovery experience.
Buprenorphine/NaloxoneBuprenorphine is an opioid medication that both acts on and blocks the euphoric and sedative effects in the brain. Naloxone is a narcotic drug that reverses the effects of other narcotic medicines when taken intravenously. Together they reduce the risk of relapse, overdose and withdrawal symptoms. Brand names include: Suboxone®, Zubsolv®, Bunavail®, Sublocade® and Cassipa®.NaltrexoneNaltrexone is a medication that blocks the euphoric and sedative effects of drugs such as heroin, morphine, hydrocodone and codeine. It comes in a pill form or as a long-acting injectable. Brand names include Vivitrol® and ReVia®.
MAT EffectivenessThe ultimate goal of MAT is full recovery, including the ability to live a self-directed life. This treatment approach has been shown to: